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Article

The aldehyde dehydrogenase 2 polymorphisms on neuropsychological performance in bipolar II disorder with or without comorbid anxiety disorder.

PloS one - 1 Jan 2018

Lu Ru-Band, Chang Yun-Hsuan, Wang Tzu-Yun, Lee Sheng-Yu, Chen Po See, Yang Yen Kuang

Abstract excerpt

Anxiety disorders (ADs), the most common comorbid illnesses with bipolar disorder (BP) has been reported to associate with dopamine system. Dopamine, metabolized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase 2 (ALDH2), and the distribution of the ALDH2*1/*1, and ALDH2*1/*2+ALDH*2/*2 alleles in the Han Chinese general population is relatively equal. The association between dopamine metabolic...

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Share to Aldehyde Dehydrogenase, Mitochondrial
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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 29425204
DOI: 10.1371/journal.pone.0192229
PMCID: PMC5806854

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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