Article
Role of DRD2 and ALDH2 genes in bipolar II disorder with and without comorbid anxiety disorder.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Mar 2014
Wang Y-S, Lee S-Y, Chen S-L, Chang Y-H, Wang T-Y, Lin S-H, Wang C-L, Huang S-Y, Lee I H, Chen P S, Yang Y K, Lu R-B
Abstract excerpt
The presence of comorbid anxiety disorders (AD) and bipolar II disorders (BP-II) compounds disability complicates treatment, worsens prognosis, and has been understudied. The genes involved in metabolizing dopamine and encoding dopamine receptors, such as aldehyde dehydrogenase 2 (ALDH2) and dopamine D2 receptor (DRD2) genes, may be important to the pathogenesis of BP-II comorbid with AD. We aimed to clarify...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.