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Article

Staging of alpha-synuclein in the olfactory bulb in a model of Parkinson's disease: cell types involved.

Movement disorders : official journal of the Movement Disorder Society - 15 Aug 2010

Ubeda-Bañon Isabel, Saiz-Sanchez Daniel, de la Rosa-Prieto Carlos, Mohedano-Moriano Alicia, Fradejas Noelia, Calvo Soledad, Argandoña-Palacios Lucia, Garcia-Muñozguren Susana, Martinez-Marcos Alino

Abstract excerpt

Impaired olfaction is an early symptom of Parkinson's disease. The underlying neuropathology likely includes alpha-synucleinopathy in the olfactory bulb at an earlier stage (Braak's stage1) than pathology in the substantia nigra, which is not observed until stage 3. In this report, we investigated the distribution and cell types affected by alpha-synuclein in the olfactory bulb of transgenic mice (2-8 months of...

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PMID: 20574962
DOI: 10.1002/mds.23197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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