Article
Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
PloS one - 21 Jun 2010
Shulman Joshua M, Chibnik Lori B, Aubin Cristin, Schneider Julie A, Bennett David A, De Jager Philip L
Abstract excerpt
BACKGROUND: Recent genetic studies have identified a growing number of loci with suggestive evidence of association with susceptibility to Alzheimer's disease (AD). However, little is known of the role of these candidate genes in influencing intermediate phenotypes associated with a diagnosis of AD, including cognitive decline or AD neuropathologic burden. METHODS/PRINCIPAL FINDINGS: Thirty-two single nucleotide...
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