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Article

Assessing the utility of intermediate phenotypes for genetic mapping of psychiatric disease.

Trends in neurosciences - 1 Dec 2014

Flint Jonathan, Timpson Nicholas, Munafò Marcus

Abstract excerpt

Intermediate phenotypes are traits positioned somewhere between genetic variation and disease. They represent a target for attempts to find disease-associated genetic variants and elucidation of mechanisms. Psychiatry has been particularly enamoured with intermediate phenotypes, due to uncertainty about disease aetiology, inconclusive results in early psychiatric genetic studies, and their appeal relative to...

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Identifiers

PMID: 25216981
DOI: 10.1016/j.tins.2014.08.007
PMCID: PMC4961231

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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