Article
Twist2: role in corneal stromal keratocyte proliferation and corneal thickness.
Investigative ophthalmology & visual science - 1 Nov 2010
Weaving Linda, Mihelec Marija, Storen Rebecca, Sosic Drazen, Grigg John R, Tam Patrick P L, Jamieson Robyn V
Abstract excerpt
PURPOSE: Twist2 is a member of a family of bHLH transcription factors critical for normal mesenchymal proliferation and differentiation. In this study, the authors analyzed the role of Twist2 in the eye and cornea through examination of a Twist2 loss-of-function mouse mutant. METHODS: Twist2 expression during eye development in the mouse was investigated using RT-PCR and mRNA slide in situ hybridization. Lineage...
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