Article
Interactions between Twist and other core epithelial-mesenchymal transition factors are controlled by GSK3-mediated phosphorylation.
Nature communications - 1 Jan 2013
Lander Rachel, Nasr Talia, Ochoa Stacy D, Nordin Kara, Prasad Maneeshi S, Labonne Carole
Abstract excerpt
A subset of transcription factors classified as neural crest 'specifiers' are also core epithelial-mesenchymal transition regulatory factors, both in the neural crest and in tumour progression. The bHLH factor Twist is among the least well studied of these factors. Here we demonstrate that Twist is required for cranial neural crest formation and fate determination in Xenopus. We further show that Twist function...
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