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Article

KLEIP deficiency in mice causes progressive corneal neovascular dystrophy.

Investigative ophthalmology & visual science - 31 May 2012

Hahn Nicole, Dietz Christian T, Kühl Sandra, Vossmerbaeumer Urs, Kroll Jens

Abstract excerpt

PURPOSE: The BTB-kelch protein KLEIP/KLHL20 is an actin binding protein that regulates cell-cell contact formation and cell migration. The aim of our study was to characterize KLEIP's function in ocular health and disease in mice. METHODS: KLEIP(-/-) mice were generated, and corneas were examined histologically and stained for keratin-1, loricrin, keratin-12, keratin-14, CD31, LYVE-1, F4/80, E-cadherin, and Ki67....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22511632
DOI: 10.1167/iovs.12-9676

Genes

KLHL20

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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