Article
MISS: a non-linear methodology based on mutual information for genetic association studies in both population and sib-pairs analysis.
Bioinformatics (Oxford, England) - 1 Aug 2010
Brunel Helena, Gallardo-Chacón Joan-Josep, Buil Alfonso, Vallverdú Montserrat, Soria José Manuel, Caminal Pere, Perera Alexandre
Abstract excerpt
MOTIVATION: Finding association between genetic variants and phenotypes related to disease has become an important vehicle for the study of complex disorders. In this context, multi-loci genetic association might unravel additional information when compared with single loci search. The main goal of this work is to propose a non-linear methodology based on information theory for finding combinatorial association...
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