Article
SNP sets selection under mutual information criterion, application to F7/FVII dataset.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2008
Brunel H, Perera A, Buil A, Sabater-Lleal M, Souto J C, Fontcuberta J, Vallverdu M, Soria J M, Caminal P
Abstract excerpt
One of the main goals of human genetics is to find genetic markers related to complex diseases. In blood coagulation process, it is known that genetic variability in F7 gene is the most responsible for observed variations in FVII levels in blood. In this work, we propose a method for selecting sets of Single Nucleotide Polymorphisms (SNPs) significantly correlated with a phenotype (FVII levels). This method...
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