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Article

ABCB1 (MDR1) polymorphisms and antidepressant response in geriatric depression.

Pharmacogenetics and genomics - 1 Aug 2010

Sarginson Jane E, Lazzeroni Laura C, Ryan Heather S, Ershoff Brent D, Schatzberg Alan F, Murphy Greer M

Abstract excerpt

OBJECTIVE: Variation in the ATP-binding cassette, subfamily B, member 1 transporter (ABCB1) (multidrug-resistance gene 1) gene has been investigated as a predictor of response to treatment with a variety of medications such as antiarrhythmics, chemotherapeutic agents, anti-HIV medications, and some psychotropics. The ABCB1 gene product, P-glycoprotein, affects the transport of drugs out of many cell types,...

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Source

Identifiers

PMID: 20555295
DOI: 10.1097/FPC.0b013e32833b593a

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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