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Article

Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide.

Pharmacogenetics and genomics - 1 Aug 2010

Duarte Julio D, Lobmeyer Maximilian T, Wang Zhiying, Chapman Arlene B, Gums John G, Langaee Taimour Y, Boerwinkle Eric, Turner Stephen T, Johnson Julie A

Abstract excerpt

STK39 was earlier implicated as a hypertension susceptibility gene and is thought to be involved in the control of Na-Cl co-transporter activity. STK39 has been implicated as a putative thiazide diuretic response gene, as Na-Cl co-transporter activity is inhibited by thiazides. Thus, we aimed to determine whether STK39 is a thiazide response gene. One hundred and ninety-five 'good' and 194 'poor' responders to...

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Identifiers

PMID: 20555294
DOI: 10.1097/FPC.0b013e32833b5958
PMCID: PMC2922977

Genes

STK39

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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