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Article

Association study of variants in two ion-channel genes (TSC and CLCNKB) and hypertension in two ethnic groups in Northwest China.

Clinica chimica acta; international journal of clinical chemistry - 1 Feb 2008

Wang Xiao-Feng, Lin Ren-Yong, Wang Shi-Zhen, Zhang Li-Ping, Qian Ji, Lu Da-Ru, Wen Hao, Jin Li

Abstract excerpt

BACKGROUND: Abnormalities in renal sodium and water retention and membrane ion transport play important roles in development of hypertension. Recently, Arg904Gln variant of thiazide-sensitive NaCl-cotransporter gene (TSC) and Thr418Ser variant of renal epithelial Cl-channel ClC-Kb gene (CLCNKB) were found implicated in the prevalence of essential hypertension (EH). The objective of this study was to examine the...

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Source

Identifiers

PMID: 17997379
DOI: 10.1016/j.cca.2007.10.017

Genes

CLCNKB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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