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Unraveling the genetic connections for mitochondrial DNA control region and breast cancer susceptibility.

Scientific reports - 9 Feb 2025

Khalid Namra, Khan Muhammad Umer, Rehman Raima, Kanwal Shamsa, Zahid Tazeen, Ghani Muhammad Usman, Iftikhar Ayesha, Ali Qurban, Javed Muhammad Arshad

Abstract excerpt

Breast cancer, a complex global health concern, has predominantly been studied for nuclear DNA variations. However, the role of mitochondrial DNA (mtDNA) haplogroups in breast cancer susceptibility, especially in Pakistan, remains underexplored. This case-control study investigates the association between mtDNA haplogroups and breast cancer in Pakistan. The study reveals a significant abundance of haplogroup M in...

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Identifiers

PMID: 39924515
DOI: 10.1038/s41598-025-89115-9
PMCID: PMC11808112

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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