Article
Global analysis of genetic variation in human arsenic (+3 oxidation state) methyltransferase (AS3MT).
Toxicology and applied pharmacology - 15 Mar 2010
Fujihara Junko, Soejima Mikiko, Yasuda Toshihiro, Koda Yoshiro, Agusa Tetsuro, Kunito Takashi, Tongu Miki, Yamada Takaya, Takeshita Haruo
Abstract excerpt
Human arsenic (+3 oxidation state) methyltransferase (AS3MT) is known to catalyze the methylation of arsenite. The objective of this study was to investigate the diversity of the AS3MT gene at the global level. The distribution of 18 single nucleotide polymorphisms (SNPs) in AS3MT was performed in 827 individuals from 10 populations (Japanese, Korean, Chinese, Mongolian, Tibetans, Sri Lankan Tamils, Sri Lankan...
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