Article
Self-reported skin color, genomic ancestry and the distribution of GST polymorphisms.
Pharmacogenetics and genomics - 1 Sept 2007
Suarez-Kurtz Guilherme, Vargens Daniela D, Struchiner Claudio J, Bastos-Rodrigues Luciana, Pena Sergio D J
Abstract excerpt
BACKGROUND AND OBJECTIVE: Skin color and self-reported ethnicity have systematically been used in the pharmacogenetic/-genomic literature as phenotypic proxies for geographical ancestry. Population admixture, however, challenges the appropriateness of this approach. We compared the effectiveness of color-based and marker-based biogeographical ancestry classifications in typing polymorphisms in GSTM1, GSTM3 and...
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