Article
Glutathione s-transferase variants in a brazilian population.
Pharmacology - 1 Jan 2009
Magno Luiz Alexandre V, Talbot Jhimmy, Talbot Teddy, Borges Santos Alex Marques, Souza Renan P, Marin Lauro J, Moreli Marcos Lázaro, de Melo Paulo R S, Corrêa Ronan X, Rios Santos Fabrício, Di Pietro Giuliano
Abstract excerpt
Recent pharmacogenomic studies have revealed significant interethnic differences in glutathione S-transferase (GST) allelic frequencies among various ethnic groups. Therefore, we have investigated GSTM1 (gene deletion), GSTT1 (gene deletion) and GSTP1 (rs1695) polymorphism frequencies in 3 Brazilian ethnic groups (n = 203). GSTM1 and GSTT1 polymorphism analyses were performed by multiplex polymerase chain...
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