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Article

Vexed by red-headed conundrums.

The Journal of investigative dermatology - 1 Jul 2010

Rees Jonathan L

Abstract excerpt

Reduced function alleles of the melanocortin 1 receptor (MC1R) lead to red hair, freckling, and sun sensitivity. They are also associated with an increased risk of skin cancer. But what pathways link gene variants with the cancer phenotype? In this issue, Robinson et al. describe their use of mouse transgenics to demonstrate that the MC1R signaling pathway influences cancer risk via mechanisms in addition to...

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PMID: 20548316
DOI: 10.1038/jid.2010.132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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