Article
Phenotypically and functionally distinct subsets contribute to the expansion of CD56-/CD16+ natural killer cells in HIV infection.
AIDS (London, England) - 31 Jul 2010
Hong Henoch S, Eberhard Johanna M, Keudel Phillip, Bollmann Benjamin A, Ahmad Fareed, Ballmaier Matthias, Bhatnagar Nupur, Zielinska-Skowronek Margot, Schmidt Reinhold E, Meyer-Olson Dirk
Abstract excerpt
OBJECTIVE: Chronic HIV infection has been associated with activation and increased turnover of natural killer (NK) cells as well as with disturbed homeostasis of the NK cell compartment, including loss of CD56(+) NK cells and accumulation of dysfunctional CD56(-)/CD16(+) NK cells. We performed a comprehensive phenotypical and functional characterization of this population. DESIGN: A cross-sectional study was...
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