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Phenotypic and functional characteristics of highly differentiated CD57+NKG2C+ NK cells in HIV-1-infected individuals.

Clinical and experimental immunology - 15 Dec 2022

Kristensen Anne B, Wragg Kathleen M, Vanderven Hillary A, Lee Wen Shi, Silvers Julie, Kent Helen E, Grant Michael D, Kelleher Anthony D, Juno Jennifer A, Kent Stephen J, Parsons Matthew S

Abstract excerpt

Natural killer (NK) cells are important anti-viral effector cells. The function and phenotype of the NK cells that constitute an individual's NK cell repertoire can be influenced by ongoing or previous viral infections. Indeed, infection with human cytomegalovirus (HCMV) drives the expansion of a highly differentiated NK cell population characterized by expression of CD57 and the activating NKG2C receptor. This...

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HIV-1
HIV Infections
Killer Cells, Natural
NK Cell Lectin-Like Receptor Subfamily C
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36053502
DOI: 10.1093/cei/uxac082
PMCID: PMC9750827

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