Article
Coordinated expansion of both memory T cells and NK cells in response to CMV infection in humans.
European journal of immunology - 1 May 2016
Bayard Charles, Lepetitcorps Hélène, Roux Antoine, Larsen Martin, Fastenackels Solène, Salle Virginie, Vieillard Vincent, Marchant Arnaud, Stern Marc, Boddaert Jacques, Bajolle Fanny, Appay Victor, Sauce Delphine
Abstract excerpt
NK cells are key players in the fight against persistent viruses. Human cytomegalovirus (HCMV) infection is associated with the presence of a population of CD16(+) CD56(dim) NKG2C(+) NK cells in both acutely and latently infected individuals. Here, we studied the nature of these terminally differentiated NK cells in different human populations infected with HCMV: healthy donors stratified by age, thymectomized...
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