Article
High CD56++CD16- natural killer (NK) cells among suboptimal immune responders after four years of suppressive antiretroviral therapy in an African adult HIV treatment cohort.
BMC immunology - 31 Jan 2014
Bayigga Lois, Nabatanzi Rose, Sekiziyivu Prossy Naluyima, Mayanja-Kizza Harriet, Kamya Moses R, Kambugu Andrew, Olobo Joseph, Kiragga Agnes, Kirimunda Sam, Joloba Moses, Nakanjako Damalie
Abstract excerpt
BACKGROUND: Up to 40% of HIV-infected individuals receiving Highly Active Antiretroviral Therapy (HAART) have poor CD4+ T-cell recovery. The role of natural killer (NK) cells in immune recovery during HAART is not well understood. We described the profiles of NK cell subsets and their expression of activating receptor, NKG2D and cytotoxicity receptor NKp46 among suboptimal immune responders to despite four years...
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