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Elevated Natural Killer Cell Activity Despite Altered Functional and Phenotypic Profile in Ugandans With HIV-1 Clade A or Clade D Infection

6 Jul 2009

Abstract excerpt

BACKGROUND AND OBJECTIVE: Natural killer (NK) cells most likely contribute toward limiting HIV-1 replication, and investigation into their function throughout the course of infection is therefore important. We here aimed to determine the state of the NK cell compartment in Ugandans with untreated HIV-1 clade A or D infection in comparison with matched uninfected controls. METHODS AND RESULTS: The function and...

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PMID: 19487954
DOI: 10.1097/qai.0b013e3181aa256e

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