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Article

A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.

Molecular cell - 11 Jun 2010

Anindya Roy, Mari Pierre-Olivier, Kristensen Ulrik, Kool Hanneke, Giglia-Mari Giuseppina, Mullenders Leon H, Fousteri Maria, Vermeulen Wim, Egly Jean-Marc, Svejstrup Jesper Q

Abstract excerpt

Transcription-coupled nucleotide excision repair (TC-NER) allows RNA polymerase II (RNAPII)-blocking lesions to be rapidly removed from the transcribed strand of active genes. Defective TCR in humans is associated with Cockayne syndrome (CS), typically caused by defects in either CSA or CSB. Here...

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Source

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Identifiers

PMID: 20541997
DOI: 10.1016/j.molcel.2010.04.017
PMCID: PMC2885502

Genes

UBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20541997-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.PMID 20541997Read ↗

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The C-terminal Region and SUMOylation of Cockayne Syndrome Group B Protein Play Critical Roles in Transcription-coupled Nucleotide Excision Repair.Semantic proximity Read ↗

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Clearance of DNA damage-arrested RNAPII is selectively impaired in Cockayne syndrome cellsSemantic proximity Read ↗

Prolonged stalling of RNA Polymerase II at DNA damage explains phenotypical differences between Cockayne and UV-sensitive syndromesSemantic proximity Read ↗

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