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Article

The C-terminal Region and SUMOylation of Cockayne Syndrome Group B Protein Play Critical Roles in Transcription-coupled Nucleotide Excision Repair.

The Journal of biological chemistry - 15 Jan 2016

Sin Yooksil, Tanaka Kiyoji, Saijo Masafumi

Abstract excerpt

Cockayne syndrome (CS) is a recessive disorder that results in deficiencies in transcription-coupled nucleotide excision repair (TC-NER), a subpathway of nucleotide excision repair, and cells from CS patients exhibit hypersensitivity to UV light. CS group B protein (CSB), which is the gene product of one of the genes responsible for CS, belongs to the SWI2/SNF2 DNA-dependent ATPase family and has an ATPase domain...

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Identifiers

PMID: 26620705
DOI: 10.1074/jbc.M115.683235
PMCID: PMC4714222

Genes

UBD

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