Article
The CTLA4 variants may interact with the IL23R- and NOD2-conferred risk in development of Crohn's disease.
BMC medical genetics - 10 Jun 2010
Hradsky Ondrej, Dusatkova Petra, Lenicek Martin, Bronsky Jiri, Nevoral Jiri, Vitek Libor, Lukas Milan, Zeniskova Ivana, Cinek Ondrej
Abstract excerpt
BACKGROUND: The CTLA4 (cytotoxic T-lymphocyte antigen 4) gene is associated with several immunopathologic diseases and because of its important immuno-regulatory role it may be considered also a plausible candidate for a genetic association with inflammatory bowel diseases. Previously published s...
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