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Article

Gene Polymorphisms of NOD2, IL23R, PTPN2 and ATG16L1 in Patients with Crohn's Disease: On the Way to Personalized Medicine?

Genes - 5 Jun 2021

Hoffmann Peter, Lamerz David, Hill Petra, Kirchner Marietta, Gauss Annika

Abstract excerpt

Genetic and environmental factors are involved in the pathogenesis of inflammatory bowel diseases (IBD). The study aimed at investigating the potential influence of single nucleotide polymorphisms (SNPs) NOD2 rs2066844, NOD2 rs2066845, NOD2 rs2066847, IL23R rs11209026, PTPN2 rs2542151, PTPN2 rs7234029, and ATG16L1 on the response to immunomodulatory therapies and disease course in Crohn's disease (CD)....

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Identifiers

PMID: 34198814
DOI: 10.3390/genes12060866
PMCID: PMC8227795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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