Article
Interaction between CTLA4 gene and IBD5 locus in Hungarian Crohn's disease patients.
International journal of colorectal disease - 1 Sept 2011
Csöngei Veronika, Járomi Luca, Sáfrány Eniko, Sipeky Csilla, Magyari Lili, Polgár Noémi, Bene Judit, Sarlós Patrícia, Lakner Lilla, Baricza Eszter, Szabó Melinda, Rappai Gábor, Melegh Béla
Abstract excerpt
BACKGROUNDS AND AIMS: The IGR2198a_1 and IGR2096a_1 variants of the IBD5 region were found to be associated with Crohn's disease (CD) in the Hungarian population, while IGR2230a_1 does not seem to confer risk for the disease. In the present study, our aim was to investigate the statistical interaction of these three IBD5 polymorphisms with the +49 A/G substitution within the cytotoxic T lymphocyte antigen-4...
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