Article
[New therapies targeting the genetic mutations responsible for different types of melanoma].
Actas dermo-sifiliograficas - 1 Jun 2010
Botella-Estrada R, Sanmartín Jiménez O
Abstract excerpt
A number of molecular alterations have been described for melanoma. Melanomas with BRAF mutations tend to be located in areas of intermittent sun exposure, whereas melanomas with KIT mutations mostly appear in acral areas, the mucosas, and areas of chronic sun exposure. Sorafenib, a BRAF inhibito...
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