Article
[Therapeutic approaches in Melanoma - a paradigm for personalized medicine].
Praxis - 25 Jul 2012
Dummer R, Goldinger S, Rinderknecht J, Eggmann N, Felderer L, Braun R, French L E
Abstract excerpt
Progress in molecular biology has facilitated a new classification for melanoma. Melanomas today are considered as a heterogeneous group of tumors. The different subtypes are characterized by specific genetic alterations, including mutations in kinase, such as B-RAF or c-kit. New medications like vemurafenib have been developed and are available for the systemic therapy of advanced melanomas in subpopulations...
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