Article
[BRAF mutation: a novel approach in targeted melanoma therapy].
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti - 1 Jan 2012
Arenbergerová M, Puzanov I
Abstract excerpt
The incidence of malignant melanoma is increasing worldwide, despite our best efforts in prevention and early detection. The locally advanced disease may be treated surgically with good results, however, metastatic melanoma is considered to be one of the most therapeutically challenging malignancies. The increasing knowledge of molecular changes in melanoma may change this picture. Malignant melanoma is not a...
Topics
- Antineoplastic Combined Chemotherapy Protocols
- Humans
- Indoles
- Melanoma
- Molecular Targeted Therapy
- Mutation
- Phosphatidylethanolamine Binding Protein
- Proto-Oncogene Proteins B-raf
- Skin Neoplasms
- Sulfonamides
- Vemurafenib