Advances in targeted therapy for melanoma.

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Article

Advances in targeted therapy for melanoma.

Clinical advances in hematology & oncology : H&O - 1 Sept 2010

Friedlander Philip, Hodi F Stephen

Abstract excerpt

Metastatic melanoma remains an aggressive malignancy conferring a very poor prognosis, and standard chemotherapeutic and immunologic treatments have not demonstrated an overall survival benefit. No molecularly targeted therapy is approved for the treatment of advanced melanoma. Melanoma is a molecularly heterogeneous malignancy, and optimal treatment in a given patient is likely to depend on the presence of...

Topics

Animals
Antineoplastic Agents
Humans
MAP Kinase Signaling System
Melanoma
Molecular Targeted Therapy
Mutation
Proto-Oncogene Proteins c-kit

Source

Open in PubMed

Identifiers

PMID: 21157411

Genes

KIT
BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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