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Article

KIT and Melanoma: Biological Insights and Clinical Implications.

Yonsei medical journal - 1 Jul 2020

Pham Duc Daniel M, Guhan Samantha, Tsao Hensin

Abstract excerpt

Melanoma, originating from epidermal melanocytes, is a heterogeneous disease that has the highest mortality rate among all types of skin cancers. Numerous studies have revealed the cause of this cancer as related to various somatic driver mutations, including alterations in KIT-a proto-oncogene encoding for a transmembrane receptor tyrosine kinase. Although accounting for only 3% of all melanomas, mutations in...

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Identifiers

PMID: 32608199
DOI: 10.3349/ymj.2020.61.7.562
PMCID: PMC7329741

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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