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Article

Phosphorylation of EB1 regulates the recruitment of CLIP-170 and p150glued to the plus ends of astral microtubules.

Oncotarget - 7 Feb 2017

Ran Jie, Luo Youguang, Zhang Yijun, Yang Yang, Chen Miao, Liu Min, Li Dengwen, Zhou Jun

Abstract excerpt

Phosphorylation of end-binding protein 1 (EB1), a key member of microtubule plus end-tracking proteins (+TIPs), by apoptosis signal-regulating kinase 1 (ASK1) has been demonstrated to promote the stability of astral microtubules during mitosis by stimulating the binding of EB1 to microtubule plus ends. However, the roles of other members of the +TIPs family in ASK1/EB1-mediated regulation of astral microtubules...

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PMID: 28039481
DOI: 10.18632/oncotarget.14222
PMCID: PMC5354776

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Phosphorylation of EB1 regulates the recruitment of CLIP-170 and p150glued to the plus ends of astral microtubules.PMID 28039481Read ↗

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