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Article

Evidence for a role of CLIP-170 in the establishment of metaphase chromosome alignment.

The Journal of cell biology - 18 May 1998

Dujardin D, Wacker U I, Moreau A, Schroer T A, Rickard J E, De Mey J R

Abstract excerpt

CLIPs (cytoplasmic linker proteins) are a class of proteins believed to mediate the initial, static interaction of organelles with microtubules. CLIP-170, the CLIP best characterized to date, is required for in vitro binding of endocytic transport vesicles to microtubules. We report here that CLIP-170 transiently associates with prometaphase chromosome kinetochores and codistributes with dynein and dynactin at...

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Identifiers

PMID: 9585405
DOI: 10.1083/jcb.141.4.849
PMCID: PMC2132766

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for a role of CLIP-170 in the establishment of metaphase chromosome alignment.PMID 9585405Read ↗

Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication.Semantic proximity Read ↗

The CLIP-170 orthologue Bik1p and positioning the mitotic spindle in yeast.Semantic proximity Read ↗

CLIP-170 interacts with dynactin complex and the APC-binding protein EB1 by different mechanisms.Semantic proximity Read ↗

Phosphorylation controls autoinhibition of cytoplasmic linker protein-170.Semantic proximity Read ↗

The microtubule-binding and coiled-coil domains of Kid are required to turn off the polar ejection force at anaphase.Semantic proximity Read ↗

Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition.Semantic proximity Read ↗

Tip1/CLIP-170 protein is required for correct chromosome poleward movement in fission yeast.Semantic proximity Read ↗

Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.Semantic proximity Read ↗

Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways.Semantic proximity Read ↗

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.Semantic proximity Read ↗

Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function.Semantic proximity Read ↗

Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis.Semantic proximity Read ↗

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