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Article

Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication.

The Journal of biological chemistry - 16 Oct 2009

Yang Xiaoming, Li Hongchang, Liu X Shawn, Deng Anping, Liu Xiaoqi

Abstract excerpt

CLIP-170, the founding member of microtubule "plus ends tracking" proteins, is involved in many critical microtubule-related functions, including recruitment of dynactin to the microtubule plus ends and formation of kinetochore-microtubule attachments during metaphase. Although it has been reported that CLIP-170 is a phosphoprotein, neither have individual phosphorylation sites been identified nor have the...

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Identifiers

PMID: 19687009
DOI: 10.1074/jbc.M109.017681
PMCID: PMC2781423

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Cdc2-mediated phosphorylation of CLIP-170 is essential for its inhibition of centrosome reduplication.PMID 19687009Read ↗

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