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Article

beta2-Adrenoceptor gene variation and systemic vasodilatation during ganglionic blockade.

The Journal of physiology - 15 Jul 2010

Hesse Christiane, Schroeder Darrell R, Nicholson Wayne T, Hart Emma C, Curry Timothy B, Penheiter Alan R, Turner Stephen T, Joyner Michael J, Eisenach John H

Abstract excerpt

Regional infusions of beta(2)-adrenoceptor (ADRB2) agonist have generally shown that individuals homozygous for Gly16 produces greater vasodilatation than those homozygous for Arg16. Systemic infusions have shown an opposite effect on systemic vascular resistance (SVR), possibly confounded by baroreflexes or interactions between single nucleotide polymorphism (SNP) positions 16 and 27. We tested the hypothesis...

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Share to Adrenergic beta-2 Receptor Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20519311
DOI: 10.1113/jphysiol.2010.190058
PMCID: PMC2916996

Genes

ADRB2

Provenance

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