Article
Genotype related differences in beta2 adrenergic receptor density and cardiac function.
Medicine and science in sports and exercise - 1 May 2006
Snyder Eric M, Hulsebus Minelle L, Turner Stephen T, Joyner Michael J, Johnson Bruce D
Abstract excerpt
INTRODUCTION: Several common polymorphisms of the beta2 adrenergic (ADRB2) have been described including a Glycine (Gly) for arginine (Arg) substitution at amino acid 16. In vivo studies have attributed phenotypic differences in the Arg16Gly polymorphism of the ADRB2 to differences in agonist-mediated desensitization. Some studies, however, have shown differences between genotype groups under non-agonist-mediated...
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