Article
beta-2 Adrenergic receptor variants affect resting blood pressure and agonist-induced vasodilation in young adult Caucasians.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 1999
Gratze G, Fortin J, Labugger R, Binder A, Kotanko P, Timmermann B, Luft F C, Hoehe M R, Skrabal F
Abstract excerpt
Recent evidence suggests that the prodownregulatory Gly16 allele of the beta-2 adrenergic receptor (beta-2 AR) is associated with essential hypertension in African Caribbeans. To further investigate the effect of the glycine (Gly)16 and arginine (Arg)16 beta-2 AR variants on hemodynamics, we investigated the agonist-mediated in vivo vasodilation in normotensive Austrian Caucasians and analyzed the results with...
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