Article
β2-Adrenoceptor gene variants affect vasopressor requirements in patients after thoracic epidural anaesthesia.
British journal of anaesthesia - 1 Mar 2014
Frey U H, Karlik J, Herbstreit F, Peters J
Abstract excerpt
BACKGROUND: While the β2-adrenoceptor pathway is essential for cardiovascular regulation, the impact of ADRB2 gene variations on circulatory responses is unclear, possibly due to neural compensatory mechanisms. We tested the hypotheses that (i) sympathetic block by thoracic epidural anaesthesia (TEA) unmasks the influence on arterial pressure of genetic variations and (ii) vasopressor requirements during TEA...
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