Article
The Gly16 Allele of the Gly16Arg Single-Nucleotide Polymorphism in the β₂-Adrenergic Receptor Gene Augments Perioperative Use of Vasopressors: A Retrospective Cohort Study.
Anesthesia and analgesia - 1 May 2016
Nielsen Morten, Staalsoe Jonatan M, Ullum Henrik, Secher Niels H, Nielsen Henning B, Olsen Niels V
Abstract excerpt
BACKGROUND: Arterial hypotension is frequent in patients undergoing anesthesia and may aggravate the outcome. Common genetic variations may influence the cardiovascular response to anesthesia. In this retrospective cohort study, we tested whether variation in the gene encoding the β2-adrenergic receptor (ADRB2) influences perioperative arterial blood pressure and consequently the use of vasopressors. METHODS:...
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