Article
Anxiolytic effect of music exposure on BDNFMet/Met transgenic mice.
Brain research - 6 Aug 2010
Li Wen-Jing, Yu Hui, Yang Jian-Min, Gao Jing, Jiang Hong, Feng Min, Zhao Yu-Xia, Chen Zhe-Yu
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) has been reported to play important roles in the modulation of anxiety, mood stabilizers, and pathophysiology of affective disorders. Recently, a single nucleotide polymorphism (SNP) in the BDNF gene (Val66Met) has been found to be associated with depression and anxiety disorders. The humanized BDNF(Met/Met) knock-in transgenic mice exhibited increased anxiety-related...
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