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Article

BDNF variant linked to anxiety-related behaviors.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Feb 2007

Hashimoto Kenji

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is the most-abundant neurotrophin in the brain. In mammals, it is synthesized as a precursor called proBDNF, which is proteolytically cleaved to generate mature BDNF. The BDNF gene is located on chromosome 11p13, and a functional single nucleotide polymorphism (SNP) of this gene has been shown to produce a valine (Val)-to-methionine (Met) substitution in the proBDNF...

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Source

Identifiers

PMID: 17226799
DOI: 10.1002/bies.20534

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans.Semantic proximity Read ↗

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