Article
A possible association of EMID2 polymorphisms with aspirin hypersensitivity in asthma.
Immunogenetics - 1 Jan 2011
Pasaje Charisse Flerida A, Kim Jeong-Hyun, Park Byung-Lae, Cheong Hyun Sub, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Hong Chein-Soo, Lee Yong Won, Lee Jae-Young, Koh In Song, Park Tae-Joon, Lee Jin-Sol, Kim Yongha, Bae Joon Seol, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
Aspirin-intolerant asthma (AIA) is an asthma phenotype characterized by the development of bronchoconstriction following ingestion of aspirin. Despite the well-defined pathological trigger, the underlying mechanisms of AIA are still unclear. With the biophysical characteristics of the human EMI domain-containing protein 2 (EMID2) gene in relation to the extracellular matrix deposition and epithelial-mesenchymal...
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