Article
Putative association of SMAPIL polymorphisms with risk of aspirin intolerance in asthmatics.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 Nov 2010
Kim Jason Yongha, Kim Jeong-Hyun, Park Byng-Lae, Cheong Hyun Sub, Park Jong Sook, Jang An Soo, Uh Soo-Taek, Choi Jae-Sung, Kim Yong-Hoon, Kim Mi-Kyeong, Choi Inseon S, Cho Sang Heon, Choi Byoung Whui, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
BACKGROUND: Aspirin-intolerant asthma (AIA), as a clinical syndrome caused by aspirin, is characterized by lung inflammation and reversible bronchoconstriction. Recently, the altered trafficking and diminished airway reactivity have been implicated in allergic airway remodeling. The stromal membrane-associated protein 1-like (SMAP1L) exerts common and distinct functions in vesicle trafficking including...
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