Article
Exonic variants associated with development of aspirin exacerbated respiratory diseases.
PloS one - 1 Jan 2014
Shin Seung-Woo, Park Byung Lae, Chang HunSoo, Park Jong Sook, Bae Da-Jeong, Song Hyun-Ji, Choi Inseon S, Kim Mi-Kyeong, Park Hea-Sim, Kim Lyoung Hyo, Namgoong Suhg, Kim Ji On, Shin Hyoung Doo, Park Choon-Sik
Abstract excerpt
Aspirin-exacerbated respiratory disease (AERD) is one phenotype of asthma, often occurring in the form of a severe and sudden attack. Due to the time-consuming nature and difficulty of oral aspirin challenge (OAC) for AERD diagnosis, non-invasive biomarkers have been sought. The aim of this study was to identify AERD-associated exonic SNPs and examine the diagnostic potential of a combination of these candidate...
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