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Article

Association analysis of tapasin polymorphisms with aspirin-exacerbated respiratory disease in asthmatics.

Pharmacogenetics and genomics - 1 Jul 2013

Cho Sung-hwan, Park Jong-Sook, Park Byung Lae, Bae Da-Jeong, Uh Soo-Taek, Kim Mi-Kyeong, Choi Inseon S, Shin Hyoung Doo, Park Choon-Sik

Abstract excerpt

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is characterized by the development of airway obstruction in asthmatic individuals following the ingestion of aspirin or other nonsteroidal anti-inflammatory drugs. TAPBP (TAP-binding protein, tapasin) is upregulated by eicosanoids, which act as potent inflammatory molecules in aspirin-related reactions. Thus, functional alterations in the TAPBP gene may...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23736108
DOI: 10.1097/FPC.0b013e328361d4bb

Genes

TAPBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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