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Article

Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus.

PloS one - 20 May 2010

Arias Armando, Perales Celia, Escarmís Cristina, Domingo Esteban

Abstract excerpt

BACKGROUND: Success of a viral infection requires that each infected cell delivers a sufficient number of infectious particles to allow new rounds of infection. In picornaviruses, viral replication is initiated by the viral polymerase and a viral-coded protein, termed VPg, that primes RNA synthesis. Foot-and-mouth disease virus (FMDV) is exceptional among picornaviruses in that its genome encodes 3 copies of VPg....

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Share to Cytopathogenic Effect, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Viral

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Source

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Identifiers

PMID: 20505767
DOI: 10.1371/journal.pone.0010735
PMCID: PMC2873979

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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