VPg gene amplification correlates with infective particle formation in foot-and-mouth disease virus.

doi:10.1128/JVI.66.4.2251-2260.1992

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Article

VPg gene amplification correlates with infective particle formation in foot-and-mouth disease virus.

Journal of virology - 1 Apr 1992

Falk M M, Sobrino F, Beck E

Abstract excerpt

In order to analyze the function of VPg amplification in aphthoviruses, we have undertaken the first mutational analysis of the repetitive VPg-coding region using an improved foot-and-mouth disease virus (FMDV) cDNA clone from which infective viral RNA was synthesized. A set of VPg mutants was co...

Topics

Aphthovirus
Exons
Gene Amplification
Genes, Viral
Kinetics
Mutagenesis, Site-Directed
Mutation
Polymerase Chain Reaction
Precipitin Tests
Protein Processing, Post-Translational
RNA, Viral
Viral Proteins
Virus Replication

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