Article
The effect of p22(phox) -930A/G, A640G and C242T polymorphisms of NADPH oxidase on peripheral and central pressures in healthy, normotensive individuals.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2010
Xaplanteris Panagiotis, Vlachopoulos Charalambos, Baou Katerina, Vassiliadou Carmen, Dima Ioanna, Ioakeimidis Nikolaos, Stefanadis Christodoulos
Abstract excerpt
The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase produces superoxide, thus regulating redox state in the vessel wall. Three single-nucleotide polymorphisms (SNPs; -930A/G, A640G and C242T) of the p22(phox) subunit have been associated with hypertension; however, their role in peripheral and central pressures in normotensive individuals has not been addressed. A total of 210 healthy, normotensive...
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